Bullet Blender是一款新颖、快速、高通量、高稳定性的组织细胞破碎仪。使用专利的试管击打技术，转头以每分钟几千次的频率击打试管，使样品在试管内产生剧烈的振动，从而达到有效的混合。在样品中加入不同规格的高耐磨性研磨珠，可对细胞或组织样品进行彻底的破碎和均质，提取样品中的核酸、蛋白、亚细胞结构或其它有机成分。避免了手工研磨、机械匀浆、超声波处理等传统方法费时、费力、效率低、效果差、重现性差和易交叉污染等缺点。同时由于其创新的设计，也成为了世界上性价比最高的大通量组织细胞破碎仪。
Bullet Blender的特点：
● 高通量样品处理能力，单次处理时间一般不超过3分钟，大大提高了实验室的工作效率；
● 不同型号分别可容纳24个1.5/2mL离心管、12个5ml离心管（Blue 5型）或8个50mL离心管（50-DX型）；
● 不需要特殊样品管，推荐使用Eppendorf的1.5mL（可液氮预冻）、2mL微量离心管和5mL离心管，BD falcon的50mL离心管，大大降低使用成本；
● 非接触式样品处理方式，整个过程中样品都保持密封，无交叉污染发生；
● 24伏直流马达，产热量小，除转头外，无其它活动部件，使用寿命更长；
● 具有强制风冷功能，降低仪器和样品的热累积，最大限度的避免核酸、蛋白质等生物活性物质因高温而降解；
● 处理时间1到5分钟和3到15分钟(50ml型)可调，或直接按启动键可进行短时间处理；
● 转头速度从低速漩涡混合到高速剧烈振动10档可选；
● 紧凑的设计，20cm (直径)×19cm(高)，只需电源即可在实验室任何一个地方使用；
● 可放置于4℃到60℃的环境中运行；
● 提供各种尺寸和材质的研磨珠，满足处理不同样品的需要；
● 对于用户的特殊样品，提供具有针对性的实验方案；
针对不同的用户，Bullet Blender具有多个型号供选择，分别是：
● Bullet Blender（BBX24）：适用1.5/2.0ml微量离心管，可同时处理24个样品，不带风冷功能；
● Bullet Blender Blue（BBX24B）：适用1.5/2.0ml微量离心管，可同时处理24个样品，带风冷功能；
● Bullet Blender（BBX24W）：适用1.5ml旋盖离心管（带密封圈），可同时处理24个样品，带风冷功能，适合处理生物危险类样品；
● Bullet Blender Blue 5（BBX5MB）：适用5.0ml离心管，可同时处理12个样品，适用于中等强度的样品，带风冷功能；
● Bullet Blender 50-DX（BB50-DX）：适用50ml离心管，可同时处理8个样品，适用于较易破碎的样品，带风冷功能；
● Field Blender（FBBX）：适用1.5/2.0ml微量离心管，内置电池，方便在野外对样品进行处理，电池驱动，一次可处理6个样品；室内通电使用，和普通型号性能一样；
● BioBox Blender（内置BBX24W）：适用1.5ml旋盖离心管（带密封圈），可同时处理24个样品，透明腔体方便观察样品处理情况，带透明外腔，可产生负压，避免因样品管意外泄漏造成气溶胶扩散，适合处理生物高致病危险样品，可随生物安全柜一起消毒；
使用Bullet Blender处理样品的部分参考文献
主动脉（小鼠）
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主动脉和肝脏（小鼠）
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膀胱和肾脏（小鼠，分离细菌）
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大脑（小鼠）
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毛虫（P. isabella）
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培养细胞 (人体)
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结肠（人体）
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结肠（小鼠）
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果蝇（Drosophila melanogaster）
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心脏(心室-小鼠)
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心脏
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钩虫(幼虫)
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肠(十二指肠和盲肠，鸡)
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肠粘膜（猪）
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肝脏和脑（大鼠）
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肝脏（鱼）
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肝脏（猴）
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肝脏（小鼠）
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肺（小鼠）
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肺（大鼠）
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微孢子虫（Microsporidia Nosema）
Bourgeois AL, Rinderer TE (2010) Genetic detection and quantification of Nosema apis and N. ceranae in the honey bee. J Inv, , ertebr Pathol 103:53-58
苔藓, , (Physcomitrella patens)
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肌肉（鱼）
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肌肉（人体）
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肌肉（小鼠）
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Welle S, Mehta S, Burgess K (2011) Effect of postdevelopmental myostatin depletion on myofibrillar protein metabolism. Am J Physiol Endocrinol Metab 300:E993-E1001
肌肉（大鼠）
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鼻息肉（人体）
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鼻粘膜（小鼠）
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咽（人体）
Winder DM, Ball SL, Vaughan K, Hanna N, Woo YL, Fränzer JT, Sterling JC, Stanley MA, Sudhoff H, Goon PK (2009) Sensitive HPV detection in oropharyngeal cancers. BMC Cancer 9:440
土豆
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小肠和回肠(豚鼠)
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皮肤（人体）
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皮肤（大鼠）
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胃（小鼠，分离幽门螺旋杆菌）
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肿瘤（小鼠）
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黑色素瘤（人体）
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胸部（蜜蜂）
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脐带和胎便（人体）
Marin SJ, Christensen RD, Baer VL, Clark CJ, McMillin GA (2011) Nicotine and metabolites in paired umbilical cord tissue and meconium specimens. Ther Drug Monit 33(1):80-5.
****（兔）
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酵母菌（C. albicans）
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酵母菌（S. cerevisiae）
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酵母菌（S. passalidarum)
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酵母菌 (S. passalidarum, P. Stipitis)
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酵母菌
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各种组织（小鼠肝脏、心脏、肌肉，分离提取病毒）
Miller BF, Robinson MM, Bruss MD, Hellerstein M, Hamilton KL (2011) A comprehensive assessment of mitochondrial protein synthesis and cellular proliferation with age and caloric restriction. Aging Cell 10.1111/j.1474-9726.2011.00769
各种组织（小鼠脊椎、大脑、胃、小肠、结肠，分离提取病毒）
Lancaster KZ, Pfeiffer JK (2010) Limited trafficking of a neurotropic virus through inefficient retrograde axonal transport and the type I interferon response. PLoS Pathog 6:e10000791
各种组织（小鼠肝脏、肌肉、脂肪、主动脉）
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